Learn More:
     + Dempsey Challenge 2021
     + Help Ease Someone's Cancer Journey
     + In-person Events
     + Registration + Fundraising
     + Connect With Us!

The Dempsey Challenge, presented by Amgen Oncology, is an annual run, walk, and cycle experience and is the primary fundraiser for the Dempsey Center. It is a weekend of celebration and remembrance when our community comes together to raise $1.5 critical funds that go directly to providing services to people impacted by cancer at no cost.


On the weekend of September 25 + 26, you will have the opportunity to participate powerfully in any way you are most comfortable. Dempsey Challenge 2021 will offer both local and global options to meet you where you are. Run, walk or ride on Dempsey Challenge weekend in Lewiston, Maine ~ OR ~ run, walk or ride in your own hometown, anywhere in the world! 

In 2020, the Dempsey Challenge was successfully reimagined as people from around the world came together to participate and support the Dempsey Center’s mission to make life better for people impacted by cancer. Together, we move forward today with the same unifying spirit as we create a new Dempsey Challenge in a new world; a Global Dempsey Challenge where we all come together on one powerful weekend in September.

Register as a Local Challenger or Global Challenger (participate anytime, anywhere, and in any way you choose). You’ll be supported and encouraged every step of the way as you complete your own Dempsey Challenge, regardless of how you choose to participate. Whether you are a returning participant or new to the Dempsey Challenge, participate powerfully

The spirit of the Dempsey Challenge lives on in all of us. Register for the 2021 Dempsey Challenge today and explore what’s possible.


The Dempsey Center provides a haven of support to cancer patients, their loved ones, and care partners. In 2020 we launched our third, virtual center-- Dempsey Connects, which not only expanded our reach in the state of Maine, but also meant that select services could now be provided beyond the borders of Maine, for anyone who needs it - all at no cost.

Dempsey Challenge weekend will continue to be a chance to engage and enlist support from friends, family, and colleagues during your fundraising outreach. You’ll be a part of a global community, whether participating in person in Lewiston or in your own backyard. With your help, we’ll raise $1.5 million that will go directly to providing services to people impacted by cancer at no cost. That’s right, it is an ambitious goal, but we know all of you are up for the Challenge.

Registration has been simplified to give you an immediate boost to your fundraising goal. Registration is now $50 for any single event you choose, and will be applied to your $250 fundraising minimum. Every registration fee now includes a t-shirt and decal to welcome you into the Dempsey Challenge community. Youth and young adult participants will enjoy a 50% discount on registration and lower or no fundraising commitments. Through your registration you will have access to a supportive and inclusive community, and to virtual training and challenge events that will be hosted throughout the summer, leading up to September 25 + 26.

We've added new and exciting fundraising incentives and opportunities to ensure you are rewarded for your efforts, no matter where you participate from. 


Many of you will have different comfort levels with participation in group activities due the COVID-19 pandemic. We want everyone to feel safe and comfortable, which is why you will be able to choose (and change) your participation for 2021. During registration, you will choose your Challenge location and confirm your plan as you get closer to event weekend. A detailed health and safety event plan based on current CDC guidelines will be provided to you to help you make your final decision about how you participate. 

NEW FOR 2021: 

To ensure proper planning for the number of people registered for our in-person event, participants who register for the Local Challenge (taking place in Lewiston/Auburn, Maine) will need to reserve your spot by meeting the fundraising minimum by September 23. If the minimum fundraising has not been met by the deadline, you forfeit your spot for the in-person Local Challenge.  We will automatically change your participation to the Global Challenge where you will be able to participate virtually.

Local Challenge participants will have the option to switch to the Global Challenge at any time, however if you wish to change from the Global Challenge to the Local Challenge, you will need to do so by September 23. Participants will be reminded several times before the September 23 deadline. At this time, we do not anticipate being able to accept any registrations for the in-person Local Dempsey Challenge after September 23. Policy subject to change.

There is no penalty if you do not hit your fundraising minimum as a Global Challenger. Questions? Contact us at [email protected]

In-person event located in Lewiston, Maine featuring 5K/10K run walk on September 25 and ride events on September 26. Virtual event you complete  anywhere and in any way you choose. Join our global community as we support people impacted by cancer. 

No matter how you participate, participate powerfully



Have fun and improve the lives of people impacted by cancer

  • Registration is $50 for any event or $75 for 2 events
  • Youth and young adult participants ages 23 & under receive registration and fundraising discounts as outlined below:
    • Young adults ages 18-23*: $25 registration which counts toward a $125 fundraising minimum
    • Youth participants ages 17 & under*: $25 registration with no fundraising minimum
    • *Age as of 9/25/2021
  • All registration fees include a t-shirt and decal
  • Incentives start at $250 and special recognition continues for higher fundraising achievements
Whether you are a local or global participant, everyone commits to fundraise to support people managing the impact of cancer.



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